Sortiva H 50 12.5Mg | 30Tab

• Sortiva H 50/12.5,

Scientific Name

• Losartan 50 Mg + Hydrochlorothiazide 12.5 Mg Tablets

Category Of Sortiva H 50/12.5 Tablets

• Anti-Hypertensive Drugs

Mechanism Of Action Of Losartan & Hydrochlorothiazide

• Losartan is an angiotensin II receptor blocker (ARB). It works by blocking a substance in the body that causes blood vessels to constrict.
• As a result, losartan relaxes the blood vessels. This lowers blood pressure and increases the supply of blood and oxygen to the heart.
• Hydrochlorothiazide inhibits sodium chloride transport in the distal convoluted tubule. More sodium is then excreted in the kidney with accompanying fluid.
• Thus it increases urine excretion, which by turn decreases blood volume and finally blood pressure.
• On long-term usage, thiazide diuretic (TZD)-mediated chronic reduction of arterial pressure is thought to occur through decreased total peripheral vascular resistance.

Therapeutic Indications Of Sortiva H 50/12.5 Tablets

• Treatment of essential hypertension.
• High blood pressure is a common condition in which the long-term force of the blood against your artery walls is high enough that it may eventually cause health problems, such as heart disease.

Method Of Administration Of Sortiva H 50/12.5 Tablets

• The tablets can be taken with or without food.
• Swallow the tablets with a sufficient amount of water (e.g. One glass).
• If possible, take your daily dose at the same time each day, for example at breakfast time.
• Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.
• The usual dose of losartan potassium and hydrochlorothiazide for most patients with high blood pressure is 1 tablet of losartan potassium and hydrochlorothiazide 50 mg/12.5 mg per day to control blood pressure over 24 hours.
• This can be increased to 2 tablets once daily of losartan / hydrochlorothiazide 50 mg/12.5 mg film-coated tablets.
• The maximum daily dose is 2 tablets per day of losartan / hydrochlorothiazide 50 mg/12.5 mg film-coated tablets.
• Doses may be changed in special conditions so always follow your doctor's or pharmacist's instructions.
• If you take more than you should, talk to a doctor or go to the hospital straight away.
• If you forget to take a dose, take it as soon as you remember it unless it is nearly time for your next dose.
• Do not take a double dose (two doses at the same time) to make up for the forgotten dose.

Undesirable Side Effects Of Sortiva H 50/12.5 Tablets

• Cough, upper airway infection, congestion in the nose, sinusitis, sinus disorder
• Diarrhea, abdominal pain, nausea, indigestion
• Muscle pain or cramps, leg pain, back pain
• Insomnia, headache, dizziness
• Weakness, tiredness, chest pain
• Increased potassium levels (which can cause an abnormal heart rhythm), decreased
• Hemoglobin levels
• Changes in kidney function including kidney failure
• Too low sugar in the blood (hypoglycemia).

Pregnancy & Breastfeeding Precautions While Taking Sortiva H 50/12.5 Tablets

• If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.